Advances in the Study of Vascular Cognitive Dysfunction

血管性认知障碍(vascular cognitive impairment, VCI)是由脑血管病及其相关危险因素引起的一种认知功能障碍，对全球老年人的健康与生活质量产生了显著影响，尤其在我国60岁及以上人群中，VCI已成为仅次于阿尔茨海默病的第二大认知障碍病因。本文综述了血管性认知障碍的病理生理机制、神经影像学、生物标志物及治疗策略等方面的最新研究进展。Vascular cognitive impairment (VCI) is a cognitive dysfunction caused by cerebrovascular disease and its related risk factors, which has a significant impact on the health and quality of life of the elderly worldwide, and has become the second most common cause of cognitive impairment after Alzheimer’s disease, especially among people aged 60 years and above in China. This article reviews the latest research progress in the pathophysiological mechanisms, neuroimaging, biomarkers, and therapeutic strategies of vascular cognitive impairment.