Cardiac Assessment of Individuals with Opioid Use Disorder under Methadone Treatment
This study demonstrated an association between methadone treatment characteristics (higher dose and longer duration) and cardiac dysfunction. These findings suggest dose- and time-dependent cardiotoxic effects of methadone. Clinicians should implement cardiac monitoring, dose minimization, and risk-reduction strategies for patients on long-term methadone therapy.
Authors
- Mansour Moazenzadeh (ORCID: https://orcid.org/0000-0002-4391-8503)
- Haleh Esmaili (ORCID: https://orcid.org/0000-0002-3750-9076)
- Hamid Reza Barkhordari
- Hamidreza Poureslami
- Mohammad Masoumi
Institutions
- Kerman University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Research in Pharmacy Practice
- Published
- 2025-04-01
- DOI
- https://doi.org/10.4103/jrpp.jrpp_15_25
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00