Adenovirus Disease and Ocular Symptoms in Children: Diagnosis and Prognostic Considerations

Adenoviral infections significantly impact pediatric health, manifesting as respiratory, gastrointestinal, and ocular disorders. We report a 14-year-old male with adenoviral pharyngoconjunctival fever (PCF) complicated by subconjunctival hemorrhage and enlarged adenoids. The patient presented with high-grade fever, sore throat, bilateral conjunctivitis, and gastrointestinal symptoms, including vomiting and diarrhea. Initial laboratory findings suggested septicemia; however, an extended respiratory panel confirmed adenoviral infection. Notably, the patient also had left-sided undescended testes and scoliosis, raising questions about potential associations. This case underscores the complexity of adenoviral infections in children, highlighting the interplay of respiratory, gastrointestinal, and ocular symptoms. The presence of additional conditions warrants further investigation into possible correlations with adenoviral infection. Comprehensive evaluation is crucial for accurate diagnosis and management of adenoviral infections in pediatric patients, and future research should explore long-term implications and associations with cryptorchidism and scoliosis.

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Publication Details

Journal
Case Reports in Infectious Diseases
Published
2025-01-01
DOI
https://doi.org/10.1155/crdi/2621782
Primary Topic
Virus-based gene therapy research
Type
article
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article

Adenovirus Disease and Ocular Symptoms in Children: Diagnosis and Prognostic Considerations

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Case Reports in Infectious Diseases
Virus-based gene therapy research
article

Adenovirus Disease and Ocular Symptoms in Children: Diagnosis and Prognostic Considerations

Tajrin Rahman, Jannatul Fardous, Mohammad Delwer Hossain Hawlader, Sarwar Hussain, Mohammad Ashraful Amin, Sabrina Nahin, Arpita Goutam, Zahid Hasan Khan, Muhammad Sikardar Ghayas Khan
article en

Abstract

Adenoviral infections significantly impact pediatric health, manifesting as respiratory, gastrointestinal, and ocular disorders. We report a 14-year-old male with adenoviral pharyngoconjunctival fever (PCF) complicated by subconjunctival hemorrhage and enlarged adenoids. The patient presented with high-grade fever, sore throat, bilateral conjunctivitis, and gastrointestinal symptoms, including vomiting and diarrhea. Initial laboratory findings suggested septicemia; however, an extended respiratory panel confirmed adenoviral infection. Notably, the patient also had left-sided undescended testes and scoliosis, raising questions about potential associations. This case underscores the complexity of adenoviral infections in children, highlighting the interplay of respiratory, gastrointestinal, and ocular symptoms. The presence of additional conditions warrants further investigation into possible correlations with adenoviral infection. Comprehensive evaluation is crucial for accurate diagnosis and management of adenoviral infections in pediatric patients, and future research should explore long-term implications and associations with cryptorchidism and scoliosis.

Case Reports in Infectious DiseasesVol. 2025(1)
University of London (GB), North South University (BD), International Centre for Diarrhoeal Disease Research (BD), Bangladesh College of Physicians and Surgeons (BD), London School of Hygiene & Tropical Medicine (GB), Prince Mohammed bin Abdulaziz Hospital (SA), National Institute of Traumatology & Orthopaedic Rehabilitation (BD), Faculty of Public Health (GB), National Institute of Cardiovascular Diseases (BD), Green Cross International (US), Dhaka Medical College and Hospital (BD)
Good health and well-being
Openalex Percentile: Top 78%
Virus-based gene therapy research
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