Post-Biperiden Myocardial Depression and Acute Pulmonary Oedema: A Case Report

Biperiden, a muscarinic receptor antagonist, is utilised in antipsychotic therapies and has been associated with a restricted incidence of cardiac side effects.This case study details a 30-year male patient who had acute pulmonary oedema and cardiac depression after a biperiden overdose.The patient arrived at the emergency department exhibiting dyspnoea, agitation, and a low oxygen saturation level of 65%.The physical examination and imaging indicated pulmonary oedema and diminished heart motion.The intervention included non-invasive ventilation, nitroglycerin infusion, and diuretics.Throughout the clinical follow-up, the patient's respiratory and cardiac symptoms exhibited improvement, with no alterations noted in troponin levels.It can be inferred that the infrequent cardiac side effects of biperiden, particularly in cases of overdose, can lead to severe consequences such as acute pulmonary oedema.Consequently, it is imperative to effectively manage this illness to avert fatality.