LONG-TERM PERSISTENCE OF THE TICK-BORNE ENCEPHALITIS AGENT IN THE HUMAN BODY

The article presents the results of long-term observations of 97 patients who had suffered various clinical forms of tick-borne encephalitis (TBE), with a long period of IgM antibody formation. The latter may indicate the persistence of the virus in the human body. Possible causes of this condition are discussed, including secondary (virus-mediated) immunodeficiency. The importance of life history and disease history in the process of differential diagnosis of residual effects of tick-borne encephalitis and progression of symptoms (chronization of the process) is also considered.The issue of the importance of life history and disease history in the process of differential diagnosis of residual effects of tick-borne encephalitis and progression of symptoms (chronization of the process) is also considered.