LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression

LMNB1 and LMNB2 are prognostic factors for HCC. GSK461364 is a novel therapeutic candidate for HCC, with anti-HCC effects associated with LMNB1/2 suppression.

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Publication Details

Journal
Recent Patents on Anti-Cancer Drug Discovery
Published
2025-08-04
DOI
https://doi.org/10.2174/0115748928375684250716120144
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
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article

LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression

Wenhao Suo, Qing Peng, Mingxin Pan, Hui Yong et al.
Recent Patents on Anti-Cancer Drug Discovery
Cancer, Hypoxia, and Metabolism
article

LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression

Wenhao Suo, Qing Peng, Mingxin Pan, Hui Yong, Rongxia Li, Xin Kang, Binhui Li, Zizhong Hu, Yingqi Zhou, Wanren Yang, Jia Yao, Botian Ouyang
article en

Abstract

LMNB1 and LMNB2 are prognostic factors for HCC. GSK461364 is a novel therapeutic candidate for HCC, with anti-HCC effects associated with LMNB1/2 suppression.

Recent Patents on Anti-Cancer Drug DiscoveryVol. 20
Third Affiliated Hospital of Southern Medical University (CN), Longgang Central Hospital (CN), Qinghai No.3 People's Hospital (CN), Chinese University of Hong Kong, Shenzhen (CN), Zhujiang Hospital (CN), University of Hong Kong - Shenzhen Hospital (CN), Qinghai Provincial Peoples Hospital (CN), Shenzhen Second People's Hospital (CN), Southern Medical University (CN)
Openalex Percentile: Top 74%
Cancer, Hypoxia, and Metabolism
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LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression — Wenhao Suo, Qing Peng, et al. · Recent Patents on Anti-Cancer Drug Discovery (2025) | TGRS Research Map | TGRS