Ctnna3 Deficiency Promotes Heart Regeneration by Enhancing Cardiomyocyte Proliferation in Neonatal Mice
Our study demonstrates that <i>Ctnna3</i> deficiency is sufficient to promote heart regeneration and cardiomyocyte proliferation in neonatal mice and indicates that functional interference of α-catenins might help to stimulate myocardial regeneration after injury.
Authors
- Wufan Tao (ORCID: https://orcid.org/0000-0002-8033-5120)
- Jifen Li (ORCID: https://orcid.org/0000-0001-8626-7707)
- Wuhou Dai
- Zeyi Cheng (ORCID: https://orcid.org/0000-0002-3800-4926)
- Hongyan Wang (ORCID: https://orcid.org/0000-0002-9422-5264)
- Sha Zou (ORCID: https://orcid.org/0000-0001-5453-6941)
Institutions
- Thomas Jefferson University (US)
- Fudan University (CN)
- Ruijin Hospital (CN)
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-07-30
- DOI
- https://doi.org/10.31083/fbl39676
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Commission of Shanghai Municipality
- National Key Research and Development Program of China