Characteristics of Adults With Non‐Hospitalized Severe Respiratory Illness: Findings From a COVID‐19 Vaccine Effectiveness Evaluation in Kenya, 2022–2023

ABSTRACT Studies suggest the burden of non‐hospitalized severe respiratory illness might be substantial in Kenya. Using data from a Kenya COVID‐19 vaccine effectiveness evaluation, we compared characteristics of patients aged ≥12 years who were hospitalized with severe respiratory illness to outpatients who were referred for hospitalization and declined (non‐hospitalized). Symptom presentation and lung radiograph findings were similar among both groups, and patients in both were diagnosed with critical conditions, including acute respiratory distress syndrome (12% hospitalized; 4% non‐hospitalized) and sepsis (10% both). Findings underscore the importance of including non‐hospitalized severe illness when estimating the burden of disease for respiratory viruses.

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Publication Details

Journal
Influenza and Other Respiratory Viruses
Published
2025-08-01
DOI
https://doi.org/10.1111/irv.70145
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Characteristics of Adults With Non‐Hospitalized Severe Respiratory Illness: Findings From a COVID‐19 Vaccine Effectiveness Evaluation in Kenya, 2022–2023

Young M. Yoo, Philip Ngere, Richard Omore, Samuel Kadivane et al.
Influenza and Other Respiratory Viruses
SARS-CoV-2 and COVID-19 Research
article

Characteristics of Adults With Non‐Hospitalized Severe Respiratory Illness: Findings From a COVID‐19 Vaccine Effectiveness Evaluation in Kenya, 2022–2023

Young M. Yoo, Philip Ngere, Richard Omore, Samuel Kadivane, Eva Leidman, Nzisa Liku, Billy Ogwel, Kathryn E. Lafond, Gideon O. Emukule, Bryan O. Nyawanda, Eric Osoro, Radhika Gharpure, Raphael O. Anyango, Sidney Ogolla, Brian O. Onyando
article en

Abstract

ABSTRACT Studies suggest the burden of non‐hospitalized severe respiratory illness might be substantial in Kenya. Using data from a Kenya COVID‐19 vaccine effectiveness evaluation, we compared characteristics of patients aged ≥12 years who were hospitalized with severe respiratory illness to outpatients who were referred for hospitalization and declined (non‐hospitalized). Symptom presentation and lung radiograph findings were similar among both groups, and patients in both were diagnosed with critical conditions, including acute respiratory distress syndrome (12% hospitalized; 4% non‐hospitalized) and sepsis (10% both). Findings underscore the importance of including non‐hospitalized severe illness when estimating the burden of disease for respiratory viruses.

Influenza and Other Respiratory VirusesVol. 19(8)
Washington State Department of Health (US), Centers for Disease Control and Prevention (US), Kenya Medical Research Institute (KE), Ministry of Health (KE), Centers for Disease Control and Prevention (KE), Washington State University (US)
Washington State University, Centers for Disease Control and Prevention
Openalex Percentile: Top 76%
SARS-CoV-2 and COVID-19 Research
DOIOpen Access PDFOpenAlex
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