Copper-catalysed regioselective <i>S</i> -alkylation and C–3(H) activation of 4-hydroxydithiocoumarins and 4-hydroxy-2 <i>H</i> -chromene-2-thione: easy access to 4-methyl-3,4-dihydrothiopyran derivatives
One-pot synthesis of 4-methyl-3,4-dihydrothiopyran derivatives is accomplished from 4-hydroxydithiocoumarins/4-hydroxy-2 H -chromene-2-thione and vinyl ethers in the presence of CuI with the formation of two C–C bonds and one C–S bond.
Authors
- Abu T. Khan
- Prasad V. Bharatam (ORCID: https://orcid.org/0000-0002-7064-8561)
- Santa Mondal (ORCID: https://orcid.org/0000-0003-4616-445X)
- Mehak Sood
- Ahmad Ali (ORCID: https://orcid.org/0000-0002-2165-2097)
Institutions
- Indian Institute of Technology Guwahati (IN)
- National Institute of Pharmaceutical Education and Research (IN)
- National Institute of Pharmaceutical Education and Research (IN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00949a
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.94