Blood Cell Count-Based Inflammatory Markers Exhibit Superior Association with Diabetic Peripheral Neuropathy Compared to Protein-Based Markers
Our findings demonstrate that the NLR, an inflammation-related marker derived from peripheral blood cell counts, is significantly associated with DPN, whereas protein-based markers did not demonstrate clear associations. These findings suggest that NLR may serve as a simple, cost-effective biomarker for identifying patients at risk for DPN. Further longitudinal studies are warranted to clarify causal relationships and evaluate its prognostic value.
Authors
- Chi‐Chang Juan (ORCID: https://orcid.org/0000-0001-5935-6675)
- Chii‐Min Hwu (ORCID: https://orcid.org/0000-0002-8209-9627)
- Yi-Hsiu Lin (ORCID: https://orcid.org/0000-0002-2557-2844)
- Tsung-Hui Wu (ORCID: https://orcid.org/0000-0002-5922-8435)
- Guanyu Su
- Fu‐Shun Ko
Institutions
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/jir.s524220
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Taipei Veterans General Hospital
- National Science and Technology Council