Adverse drug reactions following SARS-CoV-2 vaccination of 3805 healthcare workers cause substantial sick-leave and are correlated to vaccine regimen, age, sex and serological response
Based on a large cohort of health workers, our study confirms that adverse reactions after COVID-19 vaccination can lead to a substantial amount of missed work shifts, potentially causing organizational-level disturbances in staffing. There are significant differences in ADR frequencies related to vaccine type, age and sex, at overall levels not observed for other commonly used vaccines for adults.
Authors
- Tove Fall (ORCID: https://orcid.org/0000-0003-2071-5866)
- Anna-Karin Lidström
- Johan Lindbäck (ORCID: https://orcid.org/0000-0002-6473-8798)
- Fredrik Sund
- Florence van Hunsel (ORCID: https://orcid.org/0000-0001-8965-3224)
- Bo Albinsson (ORCID: https://orcid.org/0000-0002-1184-9267)
- Gabriel Westman (ORCID: https://orcid.org/0000-0001-9402-772X)
Institutions
- Uppsala University (SE)
- Uppsala University Hospital (SE)
- University of Groningen (NL)
- Netherlands Pharmacovigilance Centre Lareb (NL)
Publication Details
- Journal
- Vaccine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127553
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00