Diagnosing Type 2 Inflammation in COPD: Comparison of Blood and Sputum Eosinophil Assessment in the University of California, Los Angeles COPD Phenotyping Study
In stable COPD patients, BEC and SpE% did not correlate well, and blood- and sputum-based diagnostic criteria identified different individuals. Defining eosinophilic COPD requires a better understanding of the bio-compartment sampled, testing methods, and cut-off values used.
Authors
- John A. Belperio (ORCID: https://orcid.org/0000-0003-2379-5486)
- Tiffany Bina
- Vyacheslav Palchevskiy (ORCID: https://orcid.org/0000-0002-7973-9988)
- William LeMaster (ORCID: https://orcid.org/0000-0002-5955-2198)
- Russell G. Buhr (ORCID: https://orcid.org/0000-0001-6159-7435)
- Donald P. Tashkin (ORCID: https://orcid.org/0000-0002-5607-4872)
- Sarah Ingersoll
- Hyewon Phee (ORCID: https://orcid.org/0000-0002-1942-0414)
- Renee Wen (ORCID: https://orcid.org/0009-0007-2367-0612)
- Jonathan E. Phillips (ORCID: https://orcid.org/0000-0002-9036-649X)
- Igor Z Barjaktarevic
- Bai Jing (ORCID: https://orcid.org/0000-0002-5430-833X)
- Christopher B. Cooper
Institutions
- Amgen (United States) (US)
- University of California, Los Angeles (US)
- Vanderbilt University (US)
- University of California System (US)
- Center for the Study of Healthcare Provider Behavior (US)
- VA Greater Los Angeles Healthcare System (US)
Publication Details
- Journal
- Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
- Published
- 2025-01-01
- DOI
- https://doi.org/10.15326/jcopdf.2024.0599
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Amgen