Ancient origin of the furin sequence in the wolf F8 gene
Our results suggest that the H1645 variant in the furin-consensus sequence was likely derived after the infraorders Cynoidea and Arctoidea diverged but before the separation of the gray wolf and coyote and persists through the domestic dog.
Authors
- L. David Mech (ORCID: https://orcid.org/0000-0003-3944-7769)
- Julie M. Crudele (ORCID: https://orcid.org/0000-0003-4472-0125)
- Valder R. Arruda (ORCID: https://orcid.org/0000-0002-8100-5481)
- Benjamin J. Samelson‐Jones (ORCID: https://orcid.org/0000-0001-6772-4140)
- Joshua Siner
- Shannon Barber-Meyer
Institutions
- United States Geological Survey (US)
- University of Washington (US)
- Northern Prairie Wildlife Research Center
- University of Pennsylvania (US)
Publication Details
- Journal
- Open Veterinary Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/ovj.2025.v15.i7.32
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Minnesota Department of Natural Resources
- University of Pennsylvania
- University of Washington
- Washington Department of Fish and Wildlife
- Trent University
- National Institutes of Health
- U.S. Geological Survey
- California Department of Fish and Wildlife
- National Heart, Lung, and Blood Institute