Clonal Hematopoiesis Prevalence Years Before a Thyroid Cancer Diagnosis: A Case-Control Study
We found that individuals who later develop early-stage thyroid cancers do not have a significantly higher prevalence of CH years before their diagnosis nor carry germline cancer susceptibility variants more often than those who do not develop thyroid cancer. Larger longitudinal studies are needed to fully elucidate the impact of germline and exposures in CH etiology.
Authors
- Ahmad Basharat (ORCID: https://orcid.org/0000-0003-0785-3076)
- Jane E. Churpek (ORCID: https://orcid.org/0000-0001-7998-5479)
- Luke Zurbriggen
- Tonia C. Carter (ORCID: https://orcid.org/0000-0002-2107-7838)
- Paola Da Pozzo (ORCID: https://orcid.org/0000-0003-3715-3249)
- Neepa Shah
- John Caskey (ORCID: https://orcid.org/0000-0001-5665-524X)
- Nikhila Aimalla
- Terrie Kitchner
- Erica Reinig
- Paloma Cabral (ORCID: https://orcid.org/0000-0001-7063-5077)
- Jens C. Eickhoff (ORCID: https://orcid.org/0000-0003-0525-6462)
- Luke F. Moat
- Kristin L. Long (ORCID: https://orcid.org/0000-0002-3839-7854)
- Kyle Shoger
Institutions
- University of Wisconsin–Madison (US)
- Marshfield Clinic (US)
- Wisconsin Division of Public Health (US)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1200/po-24-00760
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- University of Wisconsin Carbone Cancer Center
- National Institutes of Health
- Institute for Clinical and Translational Research, University of Wisconsin, Madison
- National Center for Advancing Translational Sciences