Left Atrial Appendage Thrombus Prior to Ventricular Tachycardia Ablation

Catheter-based ventricular tachycardia (VT) ablation is widely recognized as a first-line treatment for patients with VT and structural heart disease. However, one major contraindication for this procedure is the presence of intraventricular thrombus, which is commonly associated with ventricular aneurysms. Furthermore, in patients with atrial fibrillation undergoing VT ablation, it is essential to rule out atrial thrombus due to the increased risk of embolic events, which may arise from catheter interactions or thrombus displacement during shocks delivered throughout the procedure. When an atrial thrombus is detected, the procedure is typically canceled, leading to a delay in VT ablation and an increased risk of recurrent VT episodes. In such scenarios, a combined strategy involving percutaneous left atrial appendage closure followed by VT ablation may present a feasible alternative, potentially allowing for the safe and effective treatment of both conditions.

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Publication Details

Journal
JACC Case Reports
Published
2025-08-01
DOI
https://doi.org/10.1016/j.jaccas.2025.104492
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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Left Atrial Appendage Thrombus Prior to Ventricular Tachycardia Ablation

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Left Atrial Appendage Thrombus Prior to Ventricular Tachycardia Ablation

Sara Vázquez‐Calvo, Iñigo Anduaga, Laura Sanchís, Ander Regueiro, Ivo Roca‐Luque, Andreu Porta‐Sánchez, Nuria Tarrela
article en

Abstract

Catheter-based ventricular tachycardia (VT) ablation is widely recognized as a first-line treatment for patients with VT and structural heart disease. However, one major contraindication for this procedure is the presence of intraventricular thrombus, which is commonly associated with ventricular aneurysms. Furthermore, in patients with atrial fibrillation undergoing VT ablation, it is essential to rule out atrial thrombus due to the increased risk of embolic events, which may arise from catheter interactions or thrombus displacement during shocks delivered throughout the procedure. When an atrial thrombus is detected, the procedure is typically canceled, leading to a delay in VT ablation and an increased risk of recurrent VT episodes. In such scenarios, a combined strategy involving percutaneous left atrial appendage closure followed by VT ablation may present a feasible alternative, potentially allowing for the safe and effective treatment of both conditions.

JACC Case ReportsVol. 30(22)
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES), Centro de Investigación Biomédica en Red (ES), Universitat de Barcelona (ES)
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Openalex Percentile: Top 68%
Atrial Fibrillation Management and Outcomes
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