Evaluation of seropositivity developed against specific antigens of Helicobacter pylori in neurodegenerative diseases

Our data on AD cases are insufficient. In PD cases, the significantly higher frequency of immunoreactivity to the Hp-p19 antigen in individuals aged ≥50 years (OR=5.570) is noteworthy. In the MS group, the significantly high detection of Hp p17 antigen and its presence as a risk factor (OR=2.646), and the significantly high detection of p26 antigen suggest the relationship between these antigens and the MS development process. However, it is a fact that new and many prospective cohort-based case-control studies are needed to reveal this more clearly.

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Publication Details

Journal
Nöro Psikiyatri Arşivi
Published
2025-01-01
DOI
https://doi.org/10.29399/npa.29038
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
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article

Evaluation of seropositivity developed against specific antigens of Helicobacter pylori in neurodegenerative diseases

Harika Öykü Dinç, Melih Tütüncü, Rüveyda Akçin, Serhat Sirekbasan et al.
Nöro Psikiyatri Arşivi
Helicobacter pylori-related gastroenterology studies
article

Evaluation of seropositivity developed against specific antigens of Helicobacter pylori in neurodegenerative diseases

Harika Öykü Dinç, Melih Tütüncü, Rüveyda Akçin, Serhat Sirekbasan, Günay Can, Hülya Apaydın, Suat Sarıbaş, Aysun Soysal, Nazan Karagöz Sakallı, Bekir Sami Kocazeybek, Melda Bozluçay
article en

Abstract

Our data on AD cases are insufficient. In PD cases, the significantly higher frequency of immunoreactivity to the Hp-p19 antigen in individuals aged ≥50 years (OR=5.570) is noteworthy. In the MS group, the significantly high detection of Hp p17 antigen and its presence as a risk factor (OR=2.646), and the significantly high detection of p26 antigen suggest the relationship between these antigens and the MS development process. However, it is a fact that new and many prospective cohort-based case-control studies are needed to reveal this more clearly.

Nöro Psikiyatri ArşiviVol. 63
Üsküdar University (TR), Bakırköy Psychiatric Hospital (TR), Istanbul University-Cerrahpaşa (TR), Sağlık Bilimleri Üniversitesi (TR), KTO Karatay University (TR), Istanbul University (TR)
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Openalex Percentile: Top 67%
Helicobacter pylori-related gastroenterology studies
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Evaluation of seropositivity developed against specific antigens of Helicobacter pylori in neurodegenerative diseases — Harika Öykü Dinç, Melih Tütüncü, et al. · Nöro Psikiyatri Arşivi (2025) | TGRS Research Map | TGRS