THE SPREAD OF GENETICALLY DETERMINED PATHOLOGY OF THE NERVOUS SYSTEM WITH AN AUTOSOMAL RECESSIVE TYPE OF INHERITANCE IN DOGS IN THE VOLGOGRAD REGION

The article presents data on the prevalence of genetically determined pathology of the nervous system with an autosomal recessive type of inheritance in dogs of various breeds in the Volgograd region.From August 2021 to March 2025, 153 dogs of 22 breeds were tested for 20 nosologies.The results were obtained from 57 males and 96 females used in breeding.The largest number of studies have been performed on the disease degenerative myelopathy (exon 2) -63 animals with no breed specificity.14 sick dogs were identified, which amounted to 22.22% and 17 healthy carriers -26.98%, respectively.A large number of studies, among breed-specific pathologies, were conducted on Charcot-Marie-Tute disease in the Miniature Schnauzer breed -20 dogs, one sick female and one female carrier of the mutant allele were diagnosed.Healthy carriers of type 4A neuronal ceroid lipofuscinosis were also identified, in the number of five animals out of seventeen.The Russian black Terrier breed has identified a female carrier of juvenile laryngeal paralysis.The study of hereditary encephalitis of pugs reliably revealed one sick male and two healthy female carriers.In the Jack Russell Terrier breed, a female was found to be a sick carrier of spinocerebellar ataxia with myocemia and/or seizures.