Efficacy of Combined Use of PELNAC and Platelet-rich Plasma in Promoting Wound Healing
The combined use of PELNAC and PRP accelerated dermis-like granulation tissue formation through increased expression of VEGF and transforming growth factor-β1, significantly improving wound healing. This combination therapy could be easily applied in clinical practice and may contribute to shortening healing times for deep dermal defects.
Authors
- Hajime Matsumine (ORCID: https://orcid.org/0000-0001-6158-1169)
- Hiroshi Fujimaki
- Yuki Hasegawa
- Yosuke Niimi (ORCID: https://orcid.org/0000-0002-4203-380X)
- Hiroyuki Sakurai (ORCID: https://orcid.org/0000-0003-2757-6571)
Institutions
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- Plastic & Reconstructive Surgery Global Open
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1097/gox.0000000000007062
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00