Analysis of the immune microenvironment in colorectal cancer with different KRAS gene subtypes
The complexity of the immune microenvironment cannot be explained by infiltration of specific cell types alone, but may arise from cell-to-cell interactions or changes in the proportion of different immune cells. However, the infiltration of FOXP3 cells and M2 macrophages probably accounts for the differences between KRAS mutant subtypes.
Authors
- Yi Tang (ORCID: https://orcid.org/0000-0001-5728-2393)
- Qingshu Li (ORCID: https://orcid.org/0000-0002-5780-7089)
- Jing Huang (ORCID: https://orcid.org/0000-0002-0814-838X)
- Shuxian Zhang (ORCID: https://orcid.org/0009-0004-2443-1830)
- Ming Li (ORCID: https://orcid.org/0000-0002-2725-353X)
- Qian Gong (ORCID: https://orcid.org/0000-0003-4004-5441)
- Yalan Wang (ORCID: https://orcid.org/0000-0001-5252-7259)
- Ming Xiao
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1186/s12885-025-14660-5
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Chongqing Medical University