Inhibition of Ferroptosis by Adipose Stem Cell-Derived Apoptotic Vesicles Enhances Angiogenesis and Accelerates Diabetic Wound Healing
Ferroptosis of endothelial cells contributes to impaired vascularization in diabetic wounds. ApoVs represent a promising cell-free therapeutic approach to mitigate ferroptosis, restore endothelial function and promote angiogenesis, offering a potential strategy for diabetic wound management.
Authors
- Jian Kuang (ORCID: https://orcid.org/0000-0001-5024-1564)
- Lele Shi
- Geng Dou (ORCID: https://orcid.org/0000-0003-1048-7636)
- Lu Zhao (ORCID: https://orcid.org/0000-0002-9831-1020)
- Hanzhe Wang (ORCID: https://orcid.org/0009-0007-6641-8118)
- Shiyu Liu (ORCID: https://orcid.org/0000-0001-7972-4527)
- Shengkai Gong (ORCID: https://orcid.org/0000-0003-2593-8508)
- Feng Ding (ORCID: https://orcid.org/0000-0001-5973-180X)
- Jiani Liu (ORCID: https://orcid.org/0000-0001-5669-0221)
- Yimin Zhao (ORCID: https://orcid.org/0009-0003-5474-702X)
- Jingyi Zhang (ORCID: https://orcid.org/0009-0006-5588-4642)
Institutions
- Air Force Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/ijn.s527475
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81