Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe

Herein, we developed a novel dual-emission fluorescent probe DFP, for the simultaneous detection of adenosine triphosphate (ATP) and nitroreductase (NTR) in living cells. This innovative dual-channel fluorescence detection approach facilitated parallel spatial mapping of NTR and ATP distributions, providing insights into the interplay between energy metabolism and redox homeostasis.

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Publication Details

Journal
Chemical Communications
Published
2025-01-01
DOI
https://doi.org/10.1039/d5cc02820e
Citations
1
Primary Topic
Electrochemical sensors and biosensors
Type
article
Field-Weighted Citation Impact
0.73
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article

Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe

Sudai Ma, Run-Tian Ma, Jinmei Wei, Li Li et al.
1 citations
Chemical Communications
Electrochemical sensors and biosensors
0.73
article

Simultaneous detection of nitroreductase and adenosine triphosphate using a dual-emission fluorescent probe

Sudai Ma, Run-Tian Ma, Jinmei Wei, Li Li, Wenting Wang, Yumei Xu, Fang Nian
article en
1 citations

Abstract

Herein, we developed a novel dual-emission fluorescent probe DFP, for the simultaneous detection of adenosine triphosphate (ATP) and nitroreductase (NTR) in living cells. This innovative dual-channel fluorescence detection approach facilitated parallel spatial mapping of NTR and ATP distributions, providing insights into the interplay between energy metabolism and redox homeostasis.

Chemical CommunicationsVol. 61(71)
Gansu Agricultural University (CN)
Affordable and clean energy
Openalex Percentile: Top 25%
Electrochemical sensors and biosensors
0.73
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