Severity‐Dependent Neuroaxonal Damage Assessed by Serum Neurofilaments in ICANS Patients Undergoing CD19‐Targeted CAR T‐Cell Therapy
Moderate-severe ICANS is associated with elevated sNfL levels by day 7 post-infusion, indicating early neuroaxonal damage and underscoring sNfL as a valuable biomarker for assessing ICANS severity.
Authors
- Samantha Feijóo (ORCID: https://orcid.org/0000-0002-1748-3200)
- Mar Tintoré
- Andreu Vilaseca (ORCID: https://orcid.org/0000-0001-8147-8505)
- Helena Ariño (ORCID: https://orcid.org/0000-0003-4036-1671)
- Xavier Montalbán (ORCID: https://orcid.org/0000-0002-0098-9918)
- Pere Barba (ORCID: https://orcid.org/0000-0001-7076-7969)
- Gloria Iacoboni (ORCID: https://orcid.org/0000-0003-0805-9288)
- Cecilia Carpio (ORCID: https://orcid.org/0000-0001-9346-0134)
- Ana Zabalza (ORCID: https://orcid.org/0000-0003-3860-5251)
- Ángela Vidal‐Jordana (ORCID: https://orcid.org/0000-0002-7270-5507)
- Nicolás Fissolo (ORCID: https://orcid.org/0000-0002-7701-9346)
- Manuel Comabella (ORCID: https://orcid.org/0000-0002-2373-6657)
- María Jesús Arévalo (ORCID: https://orcid.org/0000-0003-0626-5555)
- Mario Sánchez
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Hebron University (PS)
- Universitat Autònoma de Barcelona (ES)
- Vall d'Hebron Hospital Universitari (ES)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/ene.70305
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09