Evaluation of Right Ventricular Long-Axis Systolic Function in Patients with Obstruc-tive Sleep Apnea by Speckle Tracking Imag-ing Combined with Cervical Doppler Ultra-sound

目的：应用二维斑点追踪成像技术(2D-STI)来评价阻塞性睡眠呼吸暂停患者的右心室纵向应变。资料与方法：本研究入组62例阻塞性睡眠呼吸暂停(OSA)患者，健康志愿者30例作为对照组。根据呼吸暂停–低通气指数(AHI)将OSA组分为轻度(5 ≤ AHI 0.6)。运用2D-STI测量右心室整体纵向应变(RVGLS)、右心室游离壁纵向应变(RVFWLS)，运用彩色多普勒测量颈内动脉RI。采用Pearson相关分析法分析OSA与右心室纵向应变的关系。结果：RVGLS、RVFWLS水平随OSA严重程度的增加而降低，与对照组相比有统计学差异(P Objective: To evaluate the longitudinal strain of right ventricle in patients with obstructive sleep apnea by two-dimensional speckle tracking imaging (2D-STI). Materials and Methods: A total of 62 patients with obstructive sleep apnea (OSA) and 30 healthy volunteers were enrolled as control group. According to apnea-hypopnea index (AHI), OSA group was divided into mild (5 ≤ AHI 0.6). The whole longitudinal strain of the right ventricle (RVGLS) and the longitudinal strain of the free wall of the right ventricle (RVFWLS) were measured by 2D-STI, and the internal carotid artery RI was measured by color Doppler. The relationship between OSA and right ventricular longitudinal strain was analyzed using Pearson correlation analysis. Results: The levels of RVGLS and RVFWLS decreased with the increase of OSA severity, and there was a statistical difference compared with control group (P < 0.01). AHI was negatively correlated with TAPSE, S’, RVGLS and RVFWLS (P < 0.01), and AHI was more strongly correlated with RVGLS and RVFWLS. Conclusion: 2D-STI may be used for early evaluation of right ventricular longitudinal strain in OSA patients.