Synthesis of an anti-cancer reagent by using sulfur-based reaction

In this paper, we have reported the synthesis of an anticancer drug against breast cancer. Constitutionally, it is known as 6-{(E)-2-[4-(methylsulfonyl)phenyl]ethenyl}-1,2,3,4 tetrahydronaphthalene During the synthesis, Friedel-Crafts reaction and Grignard reaction were used. The well-known Juliya olefination was used to create the desired stereochemistry of the target molecules, which is required for their ant0-cancer activity. After the completion of synthesis, the vibrational spectroscopy-FTIR has been used to measure the vibrational modes of the target molecules as well as intermediate compounds, which provides information about structure of the drug. From the interpreted spectral data, the structure of the compound was confirmed.

Authors

Publication Details

Journal
Journal of Research in Chemistry
Published
2025-01-01
DOI
https://doi.org/10.22271/reschem.2025.v6.i1c.192
Primary Topic
Synthesis and Characterization of Heterocyclic Compounds
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Synthesis of an anti-cancer reagent by using sulfur-based reaction

Ashok K. Yadav, Sujata Kumari
Journal of Research in Chemistry
Synthesis and Characterization of Heterocyclic Compounds
article

Synthesis of an anti-cancer reagent by using sulfur-based reaction

Ashok K. Yadav, Sujata Kumari
article en

Abstract

In this paper, we have reported the synthesis of an anticancer drug against breast cancer. Constitutionally, it is known as 6-{(E)-2-[4-(methylsulfonyl)phenyl]ethenyl}-1,2,3,4 tetrahydronaphthalene During the synthesis, Friedel-Crafts reaction and Grignard reaction were used. The well-known Juliya olefination was used to create the desired stereochemistry of the target molecules, which is required for their ant0-cancer activity. After the completion of synthesis, the vibrational spectroscopy-FTIR has been used to measure the vibrational modes of the target molecules as well as intermediate compounds, which provides information about structure of the drug. From the interpreted spectral data, the structure of the compound was confirmed.

Journal of Research in ChemistryVol. 6(1)
Openalex Percentile: Top 85%
Synthesis and Characterization of Heterocyclic Compounds
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.