Synthesis of an anti-cancer reagent by using sulfur-based reaction
In this paper, we have reported the synthesis of an anticancer drug against breast cancer. Constitutionally, it is known as 6-{(E)-2-[4-(methylsulfonyl)phenyl]ethenyl}-1,2,3,4 tetrahydronaphthalene During the synthesis, Friedel-Crafts reaction and Grignard reaction were used. The well-known Juliya olefination was used to create the desired stereochemistry of the target molecules, which is required for their ant0-cancer activity. After the completion of synthesis, the vibrational spectroscopy-FTIR has been used to measure the vibrational modes of the target molecules as well as intermediate compounds, which provides information about structure of the drug. From the interpreted spectral data, the structure of the compound was confirmed.
Authors
- Ashok K. Yadav (ORCID: https://orcid.org/0000-0003-2716-0971)
- Sujata Kumari (ORCID: https://orcid.org/0000-0002-6374-8417)
Publication Details
- Journal
- Journal of Research in Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22271/reschem.2025.v6.i1c.192
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00