Synthesis and structural studies of transition metal (II) Complexes with β-lactam antibiotic-Amoxicillin

Three neutral transition metal (II) complexes with β-lactam antibiotic ligand amoxicillin have been synthesized. Three metal ions Fe (II), Ni (II) and Cu (II) ions have been taken for complexation. The newly synthesized complexes were characterized on the basis of their elemental analysis, molar conductivities, magnetic properties as well as IR, nmr and UV spectra. On the basis of these analyses, it has been confirmed that the amoxicillin acts as tridentate ligand during the complexation with transition metal (II) ions. The six and four coordinated complex with Fe (II), Ni (II) and Cu (II) ions respectively have been established on account of above mentioned analytical measurements. Solubility of the complexes has been determined by using different solvents. Melting point of the complexes was determined by the open capillary tube and hence is uncorrected.