A multiplexed electrochemical biosensor for simultaneous discrimination of cancer cell subtypes using multi-nanoparticle labeling
Herein, an electrochemical sensing detection platform based on Y shaped DNA structures and the redox properties of metal nanoparticles (MNPs) - including AgNPs, PtFeNPs, and AuNPs, was developed for simultaneous detection of distinct cancer cell types, presenting a promising avenue for early-stage and prognostic cancer diagnostics in biologically complex environments.
Authors
- Shuying Zang (ORCID: https://orcid.org/0000-0003-1940-5916)
- Pinghua Ling (ORCID: https://orcid.org/0000-0002-0289-8147)
- Lei Feng (ORCID: https://orcid.org/0000-0002-9885-9950)
- Wenwen Xu (ORCID: https://orcid.org/0000-0001-7588-5016)
- Chenlei Li (ORCID: https://orcid.org/0000-0002-6759-3846)
- Qiuting Wang (ORCID: https://orcid.org/0000-0003-3019-1429)
- Yalong Qiao
- Danjie Song
Institutions
- Anhui Normal University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04129e
- Citations
- 1
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China