A digital nonenzymatic nucleic acid amplification assay for ultrasensitive detection of cell-free microRNA in human serum
A digital, multi-layer nonenzymatic nucleic acid amplification assay (SENA) was developed for quantifying miRNA expression levels in diluted human serum samples.
Authors
- Yingmiao Liu (ORCID: https://orcid.org/0000-0003-3516-5844)
- Andrew B. Nixon (ORCID: https://orcid.org/0000-0003-3971-2964)
- William Marx (ORCID: https://orcid.org/0000-0001-9125-2884)
- Qingshan Wei (ORCID: https://orcid.org/0000-0003-1214-010X)
- Zheng Li (ORCID: https://orcid.org/0000-0001-8067-9700)
- Shengwei Zhang (ORCID: https://orcid.org/0000-0002-7660-0884)
- Tao Yu (ORCID: https://orcid.org/0000-0001-5330-2086)
- Aditi Dey Poonam
- Amy Halbing
Institutions
- North Carolina State University (US)
- Duke Medical Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Sensors & Diagnostics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5sd00057b
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- North Carolina State University