Impact of the 2021 Chronic Kidney Disease-Epidemiology Collaboration Glomerular Filtration Rate Estimating Equation on Risk of Healthcare Utilisation for Hospitalisations for Cardiovascular and Kidney Disease
Lower eGFR ascertained by the 2009-eGFRcr(ASR), 2021-eGFRcr(AS), and EKFCcr equations were independently associated with greater risks of hospitalisation for cardiovascular and kidney disease in a multi-ethnic Asian cohort. Adoption of the race-free 2021-eGFRcr(AS) equation improved prediction of hospitalisation for CKD compared to the 2009-eGFRcr(ASR) and was non-inferior in predicting hospitalisation for AMI and AKD. These findings support the use of the 2021-eGFRcr(AS) equation in clinical practice, to predict health service utilisation for hospitalisations for cardiovascular and kidney disease, aligning with global initiatives for race-neutral kidney function evaluation.
Authors
- Andrew Ang (ORCID: https://orcid.org/0009-0006-9627-7347)
- Chieh Suai Tan (ORCID: https://orcid.org/0000-0002-8850-5585)
- Jason Chon Jun Choo (ORCID: https://orcid.org/0000-0002-8477-0875)
- Jiashen Cai (ORCID: https://orcid.org/0000-0002-6988-1809)
- Ngiap Chuan Tan (ORCID: https://orcid.org/0000-0002-5946-1149)
- Cynthia Ciwei Lim (ORCID: https://orcid.org/0000-0003-0021-4861)
- Jia Liang Kwek (ORCID: https://orcid.org/0000-0001-8161-1679)
- Hanis Abdul Kadir
Institutions
- Singapore General Hospital (SG)
- SingHealth Duke-NUS Academic Medical Centre (SG)
- SingHealth Polyclinics (SG)
Publication Details
- Journal
- The Nephron journals/Nephron journals
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1159/000547627
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00