Protocol of the Comparison of Two Different Bicarbonate Replacement Fluids during Continuous Veno-Venous Hemofiltration with Regional Citrate Anticoagulation: A Prospective, Randomized, Controlled Trial
Given the broad inclusion and restricted exclusion criteria, we expect the results of the BiPhox-Trial to be broadly applicable to patients in need of CVVH with RCA in the intensive care setting. This trial aims to determine whether the use of LBF results in more stable acid-base parameters compared to HBF during CVVH with RCA in critically ill patients and may guide therapeutic decisions in clinical practice.
Authors
- Romuald Bellmann (ORCID: https://orcid.org/0000-0003-2861-3258)
- Hanno Ulmer (ORCID: https://orcid.org/0000-0001-5911-1002)
- Sarah Maier
- Timo Mayerhöfer
- Michael Joannidis (ORCID: https://orcid.org/0000-0002-6996-0881)
- Fabian Perschinka (ORCID: https://orcid.org/0000-0003-0677-8756)
- Paul Köglberger (ORCID: https://orcid.org/0000-0002-1772-5214)
- Sebastian J. Klein
Institutions
- Innsbruck Medical University (AT)
- Klinikum Wels-Grieskirchen (AT)
- Barmherzige Schwestern vom heiligen Kreuz (AT)
Publication Details
- Journal
- Blood Purification
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1159/000547401
- Citations
- 1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43