Clonal haematopoiesis is associated with protection against angina pectoris in the UK population
CHIP protected against AP, with large TET2 CHIP specifically protecting against UAP. Elevated IL-1β levels might mediate this effect via plaque stabilization.
Authors
- Xingyu Qian
- Shiyan Hu (ORCID: https://orcid.org/0000-0003-2512-0634)
- Fuqiang Tong (ORCID: https://orcid.org/0000-0002-0470-6698)
- Yidan Zheng
- Fei Li (ORCID: https://orcid.org/0000-0001-7188-4745)
- Yuqi Liu (ORCID: https://orcid.org/0000-0002-6792-5564)
- Zhe Chen (ORCID: https://orcid.org/0000-0003-2611-9635)
- Li Xu (ORCID: https://orcid.org/0000-0001-7705-5681)
- Pengning Fan
- Chen Jiang (ORCID: https://orcid.org/0000-0001-5204-8733)
- Zihao Zhou (ORCID: https://orcid.org/0000-0002-5306-9656)
- Nianguo Dong (ORCID: https://orcid.org/0000-0002-8424-1703)
- Jingyu Xu (ORCID: https://orcid.org/0000-0001-6004-2956)
- Ming Chen (ORCID: https://orcid.org/0009-0007-3572-1579)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.jare.2025.08.002
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China