Factors Predictive of Early Discontinuation of Preventive Treatment in Children With Household Exposure to Multidrug-resistant Tuberculosis
Adherence to the 250-mg levofloxacin formulation was good among young children on preventive TB therapy. Adherence support for children and caregivers, and addressing early signs of poor adherence, may enhance treatment completion.
Authors
- Hendrik Simon Schaaf (ORCID: https://orcid.org/0000-0001-5755-4133)
- Charlotte Layton
- Susan E. Purchase (ORCID: https://orcid.org/0000-0002-9629-5952)
- Suzanne Staples (ORCID: https://orcid.org/0000-0002-9049-8070)
- Faeezah Patel (ORCID: https://orcid.org/0000-0003-1503-2016)
- Thi Ngoc Chau Duong (ORCID: https://orcid.org/0000-0002-1328-1310)
- Nadia Sabet (ORCID: https://orcid.org/0000-0001-9402-0974)
- Neil Alexander Martinson (ORCID: https://orcid.org/0000-0002-0184-5705)
- James A. Seddon (ORCID: https://orcid.org/0000-0002-2296-2302)
- Lee Fairlie (ORCID: https://orcid.org/0000-0001-5327-1734)
- Anneke C Hesseling
- Joanna Brigden
Institutions
- Desmond Tutu HIV Foundation (ZA)
- Johns Hopkins University (US)
- University of Cape Town (ZA)
- University of the Witwatersrand (ZA)
- Stellenbosch University (ZA)
- Johns Hopkins Medicine (US)
- MRC Clinical Trials Unit at UCL (GB)
- Heilongjiang Center for Tuberculosis Control and Prevention (CN)
- Perinatal HIV Research Unit (ZA)
- Research Network (United States) (US)
- University College London (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-07-18
- DOI
- https://doi.org/10.1093/ofid/ofaf425
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00