Eosinophilic Esophagitis Complicated by an Esophageal Stricture in a 15‐Month‐Old Child

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disorder characterized by dysphagia, food impactions, and esophageal eosinophilia, which can lead to fibrosis and the formation of strictures. While fibrostenotic complications are relatively rare in children, studies have shown that up to 86% of adults with EoE experience dysphagia and esophageal narrowing, compared to only 6% in children. Furthermore, the incidence of stricture formation in children remains low, with reported rates of approximately 3.4%. The youngest child previously documented with this complication was 3 years old. Risk factors for fibrostenosis in EoE include older age, prolonged disease duration, and increased symptom frequency. This represents the youngest known presentation of such a case and suggests that fibrostenosis may be a distinct phenotype of the disease, rather than merely a progression from the inflammatory form. This case underscores the importance of early and thorough evaluation of EoE, given the potential for early stricture development.

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Publication Details

Journal
Case Reports in Pediatrics
Published
2025-01-01
DOI
https://doi.org/10.1155/crpe/6685350
Primary Topic
Eosinophilic Esophagitis
Type
article
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article

Eosinophilic Esophagitis Complicated by an Esophageal Stricture in a 15‐Month‐Old Child

Nidhi Rawal, Samra Blanchard, Elaine Leonard Puppa, William S. Twaddell et al.
1 links
Case Reports in Pediatrics
Eosinophilic Esophagitis
article

Eosinophilic Esophagitis Complicated by an Esophageal Stricture in a 15‐Month‐Old Child

Nidhi Rawal, Samra Blanchard, Elaine Leonard Puppa, William S. Twaddell, Anupama Kewalramani, Jennifer Hong
article en

Abstract

Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disorder characterized by dysphagia, food impactions, and esophageal eosinophilia, which can lead to fibrosis and the formation of strictures. While fibrostenotic complications are relatively rare in children, studies have shown that up to 86% of adults with EoE experience dysphagia and esophageal narrowing, compared to only 6% in children. Furthermore, the incidence of stricture formation in children remains low, with reported rates of approximately 3.4%. The youngest child previously documented with this complication was 3 years old. Risk factors for fibrostenosis in EoE include older age, prolonged disease duration, and increased symptom frequency. This represents the youngest known presentation of such a case and suggests that fibrostenosis may be a distinct phenotype of the disease, rather than merely a progression from the inflammatory form. This case underscores the importance of early and thorough evaluation of EoE, given the potential for early stricture development.

Case Reports in PediatricsVol. 2025(1)
University of Maryland, Baltimore (US)
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Openalex Percentile: Top 67%
Eosinophilic Esophagitis
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Eosinophilic Esophagitis Complicated by an Esophageal Stricture in a 15‐Month‐Old Child — Nidhi Rawal, Samra Blanchard, et al. · Case Reports in Pediatrics (2025) | TGRS Research Map | TGRS