Human Omental Mesothelial Cells Exhibit a Corneal Endothelial-Like Cell Phenotype for Tissue Engineering of a Corneal Endothelium Biomimetic
Overall, our findings show that cultured human OMC exhibit phenotypic and functional similarities to CEC. The ability of OMC to adhere to the corneal stroma and to generate a biomimetic corneal endothelium when combined with HALC highlights their potential use in corneal endothelial regeneration.
Authors
- Juan-Carlos Gómez-Rosado (ORCID: https://orcid.org/0000-0002-9467-1934)
- Bernat Soria (ORCID: https://orcid.org/0000-0002-2356-0380)
- Jorge L. Alió del Barrio (ORCID: https://orcid.org/0000-0003-2666-3366)
- Francisco J. Diaz‐Corrales (ORCID: https://orcid.org/0000-0002-5752-0205)
- Christian Claude Lachaud (ORCID: https://orcid.org/0000-0001-8698-4589)
- Benoit R. Gauthier (ORCID: https://orcid.org/0000-0001-8146-7486)
- Alejandra Rodriguez
- Luis-Cristóbal Capitán-Morales (ORCID: https://orcid.org/0000-0003-2784-1232)
Institutions
- Universitat de Miguel Hernández d'Elx (ES)
- Instituto de Salud Carlos III (ES)
- Hospital Universitario Virgen Macarena (ES)
- Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (ES)
- Miranza (ES)
- Centro Andaluz de Biología Molecular y Medicina Regenerativa (ES)
- Universidad de Sevilla (ES)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1167/iovs.66.11.7
- Citations
- 1
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36