Effects of Cholesterol Metabolism on Corneal Endothelial Dysfunction in Patients With Type 1 Diabetes
Diabetes induced CED by inhibiting SREBF2/SQLE-dependent cholesterol biosynthesis, suggesting cholesterol supplementation protects CECs from damage caused by intraocular surgery in patients with diabetes.
Authors
- Zhichao Ren (ORCID: https://orcid.org/0000-0002-1101-7823)
- Hongran Zhao (ORCID: https://orcid.org/0000-0001-8571-785X)
- Shengqian Dou (ORCID: https://orcid.org/0000-0002-8087-0115)
- Lixin Xie (ORCID: https://orcid.org/0009-0006-8117-2067)
- Zongyi Li (ORCID: https://orcid.org/0000-0002-2637-0486)
Institutions
- Xuzhou Medical College (CN)
- Shandong Eye Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1167/iovs.66.11.9
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00