Unveiling Langerhans cell histiocytosis: A rare cause of scalp lesions in pediatrics

Langerhans Cell Histiocytosis (LCH) is a rare and clinically variable condition, most commonly affecting children. While bone involvement is frequent, cranial presentations remain a diagnostic challenge due to their overlap with other pathologies. We report the case of a 2-year-old boy presenting with multiple scalp masses, highlighting the role of imaging and histopathological analysis in the diagnosis and management of this rare disease. Additionally, we discuss the differential diagnoses and review the latest clinical guidelines for the management of pediatric LCH.

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Publication Details

Journal
Radiology Case Reports
Published
2025-08-05
DOI
https://doi.org/10.1016/j.radcr.2025.05.006
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Unveiling Langerhans cell histiocytosis: A rare cause of scalp lesions in pediatrics

Latifa Chat, El Mahdi Ait Belhaj, A. Hamzi, Siham El Haddad et al.
Radiology Case Reports
Histiocytic Disorders and Treatments
article

Unveiling Langerhans cell histiocytosis: A rare cause of scalp lesions in pediatrics

Latifa Chat, El Mahdi Ait Belhaj, A. Hamzi, Siham El Haddad, Nazik Allali, Karima Sif Nasr
article en

Abstract

Langerhans Cell Histiocytosis (LCH) is a rare and clinically variable condition, most commonly affecting children. While bone involvement is frequent, cranial presentations remain a diagnostic challenge due to their overlap with other pathologies. We report the case of a 2-year-old boy presenting with multiple scalp masses, highlighting the role of imaging and histopathological analysis in the diagnosis and management of this rare disease. Additionally, we discuss the differential diagnoses and review the latest clinical guidelines for the management of pediatric LCH.

Radiology Case ReportsVol. 20(10)
Mohammed V University (MA), Centre Hospitalier Ibn Sina (MA)
Zero hunger
Openalex Percentile: Top 75%
Histiocytic Disorders and Treatments
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