Lumbar spine infection caused by candida albicans: A case report
• Rare lumbar spine infection caused by Candida albicans diagnosed via biopsy. • Chronic low back pain as the key symptom of Candida vertebral infection. • Azole antifungal therapy effective; surgical indications remain controversial. Lumbar spine infection caused by Candida albicans is a rare condition in clinical practice that often presents as chronic lower back pain. The combination of imaging and laboratory tests can aid in the accurate diagnosis of this disease. A 75-year-old female patient reported to a physician with complaints of low back pain, numbness, and weakness in both lower extremities for one month. Despite receiving anti-inflammatory analgesia and nerve nutrition treatment, there was no improvement and the patient occasionally developed high fever and chills. After the surgical intervention and anti-infection treatment, the symptoms disappeared and the outcome was satisfactory. Chronic low back pain is a characteristic symptom of lumbar spine infection caused by Candida albicans. Pathological biopsy remains the gold standard for its diagnosis. Conservative treatment using azoles is effective, while surgical management remains controversial.
Authors
- Qunwei Dong
- Dongping Wang (ORCID: https://orcid.org/0000-0002-4705-8774)
- Jian Wang (ORCID: https://orcid.org/0000-0002-9589-4056)
- Jianxin Zhang (ORCID: https://orcid.org/0000-0001-6076-5433)
- Jie Chen (ORCID: https://orcid.org/0000-0002-4018-2502)
- Jianxian Luo (ORCID: https://orcid.org/0000-0002-0736-729X)
- Hui Zhu
- Jianbiao Huang
Institutions
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Pingliang People's Hospital (CN)
Publication Details
- Journal
- Interdisciplinary Neurosurgery
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.inat.2025.102110
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00