Incidental Findings in Clinical Practice: A Case of Hepatic Encephalopathy and Subsequent Lung Cancer Detection

Altered mental status (AMS) poses a challenge for healthcare providers due to its extensive differential diagnosis. A 67-year-old female patient with a complex medical history was admitted to the hospital due to AMS stemming from hepatic encephalopathy. During her evaluation, a routine chest X-ray revealed a right upper lobe pulmonary nodule, which was subsequently diagnosed as non-small cell lung cancer following further imaging and biopsy. This case emphasizes the importance of comprehensive assessments of incidental findings. The unanticipated identification of lung cancer in this instance underscores the critical role of early detection and a holistic diagnostic strategy, especially in populations at heightened risk, to inform effective management and enhance patient outcomes.

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Publication Details

Journal
Cureus
Published
2025-07-18
DOI
https://doi.org/10.7759/cureus.88245
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Incidental Findings in Clinical Practice: A Case of Hepatic Encephalopathy and Subsequent Lung Cancer Detection

Eric Ernest, Peter Shih
Cureus
Liver Disease and Transplantation
article

Incidental Findings in Clinical Practice: A Case of Hepatic Encephalopathy and Subsequent Lung Cancer Detection

Eric Ernest, Peter Shih
article en

Abstract

Altered mental status (AMS) poses a challenge for healthcare providers due to its extensive differential diagnosis. A 67-year-old female patient with a complex medical history was admitted to the hospital due to AMS stemming from hepatic encephalopathy. During her evaluation, a routine chest X-ray revealed a right upper lobe pulmonary nodule, which was subsequently diagnosed as non-small cell lung cancer following further imaging and biopsy. This case emphasizes the importance of comprehensive assessments of incidental findings. The unanticipated identification of lung cancer in this instance underscores the critical role of early detection and a holistic diagnostic strategy, especially in populations at heightened risk, to inform effective management and enhance patient outcomes.

CureusVol. 17(7)
Emerald Coast Science Center (US), Edward Via College of Osteopathic Medicine (US)
Good health and well-being
Openalex Percentile: Top 72%
Liver Disease and Transplantation
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Incidental Findings in Clinical Practice: A Case of Hepatic Encephalopathy and Subsequent Lung Cancer Detection — Eric Ernest, Peter Shih · Cureus (2025) | TGRS Research Map | TGRS