Prevalence of Vitamin B12 Deficiency in Type 2 Diabetic Patients on Long-Term Metformin Therapy
The study reveals a high prevalence of vitamin B12 deficiency among T2DM patients on long-term metformin therapy. The deficiency is significantly associated with older age, obesity, longer diabetes duration, and extended metformin use. Routine screening and early supplementation of vitamin B12 should be considered in diabetic patients on prolonged metformin treatment to prevent potential complications.
Authors
- Torben Francis
- Roshan Kumar Mahato (ORCID: https://orcid.org/0009-0009-9434-1650)
- Kurnia A. Kamil (ORCID: https://orcid.org/0000-0001-7942-0646)
- Hayat Ullah (ORCID: https://orcid.org/0000-0003-3833-1457)
- Shahriar Kamal
- Felicita M Tayong
- Jestin Kj
Institutions
- Tulane University (US)
- Karachi Medical and Dental College (PK)
- University of the West Indies System (JM)
- Pokhara University (NP)
- Lady Reading Hospital (PK)
- Aga Khan University Hospital (PK)
- All Saints Hospital (ZA)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-07-18
- DOI
- https://doi.org/10.7759/cureus.88265
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00