ASSESSMENT OF PEAK INSPIRATORY FLOW FOR OPTIMAL INHALER DEVICE SELECTION IN COPD PATIENTS: A CROSS-SECTIONAL STUDY

Background: Inhaled therapy remains the cornerstone of COPD management. Peak Inspiratory Flow (PIF) is a critical determinant in the appropriate use of dry powder inhalers (DPIs).Failure to match the device to the patients PIF may result in subtherapeutic outcomes. Objective: To evaluate the PIF among COPD patients and assess its implication in selecting the most suitable inhaler device. Methods: A cross-sectional observational study was conducted among 50 COPD patients attending Department of Pulmonary medicine OPD, Santhiram Medical College and General Hospital, Nandyal. PIF(Peak inspiratory flow) was measured using the In-Check DIAL device adjusted to match common inhaler resistance. Data were analyzed for correlation with age, severity of disease (GOLD stage), and inhaler technique. Results: 36% of patients had suboptimal PIF (60 L/min) for high-resistance DPIs. Suboptimal PIF was significantly associated with older age and higher GOLD stage (p 0.05). Conclusion: A significant proportion of COPD patients had inadequate inspiratory flow for effective DPI use. Routine PIF assessment should be integrated into inhaler device selection to ensure optimal therapeutic benefit.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-06-30
DOI
https://doi.org/10.21474/ijar01/21244
Primary Topic
Inhalation and Respiratory Drug Delivery
Type
article
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article

ASSESSMENT OF PEAK INSPIRATORY FLOW FOR OPTIMAL INHALER DEVICE SELECTION IN COPD PATIENTS: A CROSS-SECTIONAL STUDY

Paavani Reddy, D. Pravalika
1 links
International Journal of Advanced Research
Inhalation and Respiratory Drug Delivery
article

ASSESSMENT OF PEAK INSPIRATORY FLOW FOR OPTIMAL INHALER DEVICE SELECTION IN COPD PATIENTS: A CROSS-SECTIONAL STUDY

Paavani Reddy, D. Pravalika
article en

Abstract

Background: Inhaled therapy remains the cornerstone of COPD management. Peak Inspiratory Flow (PIF) is a critical determinant in the appropriate use of dry powder inhalers (DPIs).Failure to match the device to the patients PIF may result in subtherapeutic outcomes. Objective: To evaluate the PIF among COPD patients and assess its implication in selecting the most suitable inhaler device. Methods: A cross-sectional observational study was conducted among 50 COPD patients attending Department of Pulmonary medicine OPD, Santhiram Medical College and General Hospital, Nandyal. PIF(Peak inspiratory flow) was measured using the In-Check DIAL device adjusted to match common inhaler resistance. Data were analyzed for correlation with age, severity of disease (GOLD stage), and inhaler technique. Results: 36% of patients had suboptimal PIF (60 L/min) for high-resistance DPIs. Suboptimal PIF was significantly associated with older age and higher GOLD stage (p 0.05). Conclusion: A significant proportion of COPD patients had inadequate inspiratory flow for effective DPI use. Routine PIF assessment should be integrated into inhaler device selection to ensure optimal therapeutic benefit.

International Journal of Advanced ResearchVol. 13(06)
Openalex Percentile: Top 70%
Inhalation and Respiratory Drug Delivery
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