Albumin Dialysis Modeling Predicts the Impact of Polysulfone Dialyzers and Flow Rate on Cholic Acid and Indoxyl Sulfate Removal
Background: Cholic acid (CA) and indoxyl sulfate (IS) are toxins associated with biliary and renal disease, respectively. Protein binding prevents removal by traditional dialysis. Dissolving binding molecules such as albumin in dialysate enables detox
Authors
- Zhiquan Shu (ORCID: https://orcid.org/0000-0002-9261-5832)
- Nanye Du
- Shaohang Hao
- Martin Sadı́lek
- Alexander Novokhodko (ORCID: https://orcid.org/0000-0002-8975-6730)
- Suhail Ahmad (ORCID: https://orcid.org/0000-0003-3492-4781)
- Ziyuan Wang (ORCID: https://orcid.org/0009-0001-1959-9346)
- Dayong Gao
Institutions
- University of Washington (US)
- University of Washington Tacoma (US)
Publication Details
- Published
- 2025-07-19
- DOI
- https://doi.org/10.22541/au.175290862.23865363/v1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00