NCCN Guidelines® Insights: Uterine Neoplasms, Version 3.2025
The NCCN Guidelines for Uterine Neoplasms provide recommendations for diagnostic workup, clinical staging, and treatment options for patients with endometrial cancer and uterine sarcoma. The NCCN Cervical Uterine Panel meets at least annually to review comments from reviewers within their institutions; examine relevant new data from publications, abstracts, and recent FDA approvals; and reevaluate and update recommendations. These NCCN Guidelines Insights summarize the panel's deliberations on the new FIGO 2023 staging system and updates on the new systemic therapy recommendations for the management of endometrial cancer.
Authors
- Larissa Nekhlyudov (ORCID: https://orcid.org/0000-0001-6747-4209)
- Nadeem R. Abu‐Rustum (ORCID: https://orcid.org/0000-0001-9689-1298)
- Emma L. Barber (ORCID: https://orcid.org/0000-0002-8111-0767)
- Robert Giuntoli (ORCID: https://orcid.org/0000-0003-1232-673X)
- Ritu Salani (ORCID: https://orcid.org/0000-0002-8907-0966)
- Gina Mantia-Smaldone (ORCID: https://orcid.org/0000-0001-8223-3059)
- Nicole R. McMillian
- Stefanie Ueda (ORCID: https://orcid.org/0000-0002-4359-0966)
- Emily Wyse (ORCID: https://orcid.org/0000-0002-9657-0870)
- Scott M. Schuetze (ORCID: https://orcid.org/0000-0002-7167-4163)
- Marta A. Crispens (ORCID: https://orcid.org/0000-0002-2334-0011)
- Jayanthi Lea (ORCID: https://orcid.org/0000-0002-8657-4309)
- Stéphanie Gaillard (ORCID: https://orcid.org/0000-0002-2174-3693)
- Susana M. Campos (ORCID: https://orcid.org/0000-0001-9672-473X)
- Kristin Bradley (ORCID: https://orcid.org/0000-0002-8861-2225)
- Nita K. Lee (ORCID: https://orcid.org/0000-0002-7384-9975)
- Brooke E. Howitt (ORCID: https://orcid.org/0000-0002-0309-6680)
- Rebecca C. Arend (ORCID: https://orcid.org/0000-0003-2108-3426)
- Junzo Chino (ORCID: https://orcid.org/0000-0002-3633-9685)
- Pamela T. Soliman (ORCID: https://orcid.org/0000-0002-8784-9212)
- Renata R. Urban (ORCID: https://orcid.org/0000-0001-8967-3794)
- David K. Gaffney (ORCID: https://orcid.org/0000-0002-5752-1611)
- Kerry J. Rodabaugh (ORCID: https://orcid.org/0000-0002-8884-7083)
- Chika Nwachukwu (ORCID: https://orcid.org/0000-0001-9732-9352)
- Rachel Sisodia
- Mirna Podoll
- Andrea Mariani
- David G. Mutch (ORCID: https://orcid.org/0000-0002-6921-1581)
- John O. Schorge
- Christine M. Fisher (ORCID: https://orcid.org/0000-0001-9629-5998)
- Jean Siedel (ORCID: https://orcid.org/0000-0002-2596-3634)
- Shari Damast (ORCID: https://orcid.org/0000-0001-9030-0872)
- Scott Glaser (ORCID: https://orcid.org/0000-0002-0756-9449)
- Christa Irene Nagel (ORCID: https://orcid.org/0000-0001-6454-6246)
- Rebecca Brooks
- Lisa M. Landrum (ORCID: https://orcid.org/0000-0002-4010-6833)
- Peter J. Frederick
- Hye Sook Chon
- Sudha Amarnath
- Karina Nieto
- Vaishnavi Sambandam
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- City Of Hope National Medical Center (US)
- St. Jude Children's Research Hospital (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Tennessee Health Science Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Patient Advocate Foundation (US)
- Dana-Farber Brigham Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2025-08-01
- DOI
- https://doi.org/10.6004/jnccn.2025.0038
- Citations
- 21
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 43.20
Funders
- National Comprehensive Cancer Network