Breast Cancer Hormone Therapy Modulates Breast Implant Capsular Contracture

Patients who underwent implant-based reconstruction had reduced rates of capsular contracture if they received tamoxifen therapy at the time of implantation. These findings support preclinical models that indicate a role for local delivery of hormone therapy around implants to deliberately reduce the occurrence of capsular contracture.

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Publication Details

Journal
Plastic & Reconstructive Surgery Global Open
Published
2025-08-01
DOI
https://doi.org/10.1097/gox.0000000000007017
Primary Topic
Breast Implant and Reconstruction
Type
article
Field-Weighted Citation Impact
0.00
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article

Breast Cancer Hormone Therapy Modulates Breast Implant Capsular Contracture

Kevin M. Blum, Jenny C. Barker, Gabriel Mirhaidari, Mehak Chawla
Plastic & Reconstructive Surgery Global Open
Breast Implant and Reconstruction
article

Breast Cancer Hormone Therapy Modulates Breast Implant Capsular Contracture

Kevin M. Blum, Jenny C. Barker, Gabriel Mirhaidari, Mehak Chawla
article en

Abstract

Patients who underwent implant-based reconstruction had reduced rates of capsular contracture if they received tamoxifen therapy at the time of implantation. These findings support preclinical models that indicate a role for local delivery of hormone therapy around implants to deliberately reduce the occurrence of capsular contracture.

Plastic & Reconstructive Surgery Global OpenVol. 13(8)
Nationwide Children's Hospital (US), The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 67%
Breast Implant and Reconstruction
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