Enormous high-grade carcinoma arising from a pleomorphic adenoma in the parotid gland: A case report

CXPA, despite its aggressive nature, can often be managed without extensive resection or nerve sacrifice. In cases where neck dissection is not feasible, radiotherapy can be an effective treatment. Future research into the genetic basis and targeted therapies for CXPA is essential to enhance personalized treatment strategies and improve outcomes for patients with this complex malignancy.

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Publication Details

Journal
International Journal of Surgery Case Reports
Published
2025-08-05
DOI
https://doi.org/10.1016/j.ijscr.2025.111765
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Enormous high-grade carcinoma arising from a pleomorphic adenoma in the parotid gland: A case report

Zeinab Bakhtiari, Ata Garajei, Zahra Sadat Modarresi, Ali Nazarpour Yousefdeh
International Journal of Surgery Case Reports
Salivary Gland Tumors Diagnosis and Treatment
article

Enormous high-grade carcinoma arising from a pleomorphic adenoma in the parotid gland: A case report

Zeinab Bakhtiari, Ata Garajei, Zahra Sadat Modarresi, Ali Nazarpour Yousefdeh
article en

Abstract

CXPA, despite its aggressive nature, can often be managed without extensive resection or nerve sacrifice. In cases where neck dissection is not feasible, radiotherapy can be an effective treatment. Future research into the genetic basis and targeted therapies for CXPA is essential to enhance personalized treatment strategies and improve outcomes for patients with this complex malignancy.

International Journal of Surgery Case ReportsVol. 134(C)
Imam Khomeini Hospital (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 67%
Salivary Gland Tumors Diagnosis and Treatment
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Enormous high-grade carcinoma arising from a pleomorphic adenoma in the parotid gland: A case report — Zeinab Bakhtiari, Ata Garajei, et al. · International Journal of Surgery Case Reports (2025) | TGRS Research Map | TGRS