Mitotane-Induced Endocrine Alterations in Children with Adrenocortical Carcinoma: Clinical Implications from a 20-Year Retrospective Study
Mitotane therapy in pediatric ACC is strongly associated with significant endocrine dysfunction. These findings emphasize the need for proactive, multidisciplinary endocrine management throughout treatment.
Authors
- Stefano Vallero (ORCID: https://orcid.org/0000-0001-5561-9263)
- Luisa De Sanctis (ORCID: https://orcid.org/0000-0003-2113-6196)
- Gerdi Tuli (ORCID: https://orcid.org/0000-0001-5862-8958)
- Jessica Munarin (ORCID: https://orcid.org/0000-0002-5075-8448)
- Matilde Piglione
- Eleonora Biasin
- Franca Fagioli (ORCID: https://orcid.org/0000-0002-9257-900X)
Institutions
- 5T Torino (Italy) (IT)
- Ospedale Regina Margherita (IT)
- University of Turin (IT)
Publication Details
- Journal
- Children
- Published
- 2025-08-05
- DOI
- https://doi.org/10.3390/children12081031
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00