CircRHBDD1(4,5)/CCL2 mRNA interaction promotes breast cancer bone metastasis via bone metastatic niche formation
We revealed a credible mechanism for circRHBDD1(4,5)-induced breast cancer-bone metastasis and hypothesized that disrupting circRHBDD1(4,5)-CCL2 mRNA interactions could be a promising strategy for treating breast cancer bone metastases.
Authors
- Yingru Xu (ORCID: https://orcid.org/0009-0009-4599-1876)
- Man Li (ORCID: https://orcid.org/0000-0002-7806-1378)
- Zunfu Ke (ORCID: https://orcid.org/0000-0002-6251-7246)
- Ruyuan Yu (ORCID: https://orcid.org/0000-0001-6758-4395)
- Jun Li (ORCID: https://orcid.org/0000-0003-0572-1344)
- Xuexin Yu
- Xincheng Li (ORCID: https://orcid.org/0000-0001-5159-7036)
- Shengyuan Zhang (ORCID: https://orcid.org/0009-0002-8741-8567)
Institutions
- Sun Yat-sen University (CN)
- Jiaying University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.lfs.2025.123885
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00