Interaction Between Statin Use, Coronary Artery Disease Phenotypes, on Computed Tomography Angiography, and Cardiovascular Outcomes
Statin efficacy to decrease MACE depends on CAD phenotypes and increases with the extent and severity of disease and in the presence of high-risk plaques. Patients without CAD have no benefit from statin therapy regarding MACE. Coronary CTA may play a pivotal role in optimizing statin allocation for personalized treatment decisions to prevent MACE.
Authors
- Márton Kolossváry (ORCID: https://orcid.org/0000-0002-5570-991X)
- Ibolya Fábián
- Melinda Boussoussou (ORCID: https://orcid.org/0000-0002-0798-4319)
- Bálint Szilveszter (ORCID: https://orcid.org/0000-0003-1530-4288)
- György Rokszin (ORCID: https://orcid.org/0009-0002-0568-001X)
- Judit Simon (ORCID: https://orcid.org/0000-0001-8063-3462)
- Milán Nagy-Vecsey
- Béla Péter Merkely (ORCID: https://orcid.org/0000-0001-6514-0723)
- Pál Maurovich‐Horvat (ORCID: https://orcid.org/0000-0003-0885-736X)
- Borbála Vattay
Institutions
- Semmelweis University (HU)
Publication Details
- Journal
- JACC. Cardiovascular imaging
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.jcmg.2025.05.018
- Citations
- 4
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- Magyar Tudományos Akadémia
- Nemzeti Kutatási és Technológiai Hivatal
- Emberi Eroforrások Minisztériuma
- FP7 Coordination of Research Activities