Clinical course of patients with bloodstream infections enrolled in the BALANCE clinical trial
Among hospitalized patients with BSI, recovery trajectories were similar in patients assigned to 7- versus 14-day antibiotic treatment durations but were different comparing survivors versus non-survivors. These data could be used to inform daily clinical management, formulate predictive risk scores or clinical decision rules, and guide future research into individualized therapeutic strategies.
Authors
- Sean Wei Xiang Ong (ORCID: https://orcid.org/0000-0002-8570-436X)
- Steven Y. C. Tong (ORCID: https://orcid.org/0000-0002-1368-8356)
- Ruxandra Pinto (ORCID: https://orcid.org/0000-0003-3712-4624)
- Robert Fowler (ORCID: https://orcid.org/0000-0002-1002-2989)
- Asgar Rishu
- Nick Daneman
Institutions
- The Royal Melbourne Hospital (AU)
- Sunnybrook Health Science Centre (CA)
- The University of Melbourne (AU)
- University of Toronto (CA)
- Health Sciences Centre (CA)
- Peter Doherty Institute (AU)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1093/jac/dkaf294
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Government of Ontario
- Ontario Ministry of Health and Long-Term Care
- University of Melbourne
- University of Toronto
- Canadian Institutes of Health Research
- Medical Research Council
- National Medical Research Council
- Health Research Council of New Zealand