Effects of Obesity on Response to Asthma Biologic Treatment: Longitudinal Data From the United Kingdom Severe Asthma Registry
Asthma biologic agents appear to have important clinical benefits across the spectrum of BMI. However, because patients with obesity start at a worse baseline with respect to symptoms and exacerbations, they are still more likely to remain uncontrolled after treatment.
Authors
- Thomas Brown (ORCID: https://orcid.org/0000-0001-7336-4719)
- Mitesh Patel (ORCID: https://orcid.org/0000-0003-3975-4689)
- Liam Gabriel Heaney (ORCID: https://orcid.org/0000-0002-9176-5564)
- Adel Mansur (ORCID: https://orcid.org/0000-0002-8615-8778)
- Matthew Masoli (ORCID: https://orcid.org/0000-0003-0909-0148)
- Thomas Pantin
- John Busby (ORCID: https://orcid.org/0000-0003-4831-7464)
- Hassan Burhan (ORCID: https://orcid.org/0000-0002-5521-0748)
- Hitasha Rupani (ORCID: https://orcid.org/0000-0002-0150-138X)
- Shoaib Faruqi (ORCID: https://orcid.org/0000-0002-3159-699X)
- Martin Doherty (ORCID: https://orcid.org/0000-0002-4314-7892)
- Sherif Gonem (ORCID: https://orcid.org/0000-0002-6080-2246)
- Simon Message
- Paul Pfeffer
- D. J. Jackson (ORCID: https://orcid.org/0000-0001-6227-8524)
- Deepak Subramanian (ORCID: https://orcid.org/0000-0001-7109-6714)
- David Sammut
- Charlene Redmond (ORCID: https://orcid.org/0000-0002-5595-0308)
- Rekha Chaudhuri (ORCID: https://orcid.org/0000-0001-8007-949X)
- Pujan Patel (ORCID: https://orcid.org/0000-0002-0064-9075)
- Aashish Vyas (ORCID: https://orcid.org/0000-0002-4516-8021)
- Elfatih Idris
- Shamsa Naveed
Institutions
- Queen's University Belfast (GB)
- Belfast Health and Social Care Trust (GB)
- Lancashire Teaching Hospitals NHS Foundation Trust (GB)
- University Hospitals Birmingham NHS Foundation Trust (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University of Liverpool (GB)
- Queen Mary University of London (GB)
- University of Hull (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Barts Health NHS Trust (GB)
- Aintree University Hospitals NHS Foundation Trust (GB)
- Royal Devon & Exeter NHS Foundation Trust (GB)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Hull University Teaching Hospitals NHS Trust (GB)
- University Hospitals of North Midlands NHS Trust (GB)
- Dudley Group NHS Foundation Trust (GB)
- Gartnavel General Hospital (GB)
- University Hospitals of Leicester NHS Trust (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- Portsmouth Hospitals NHS Trust (GB)
- Manchester University NHS Foundation Trust (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Gloucestershire Health and Care NHS Foundation Trust (GB)
- Nottingham Biomedical Research Centre (GB)
- University Hospitals of Derby and Burton NHS Foundation Trust (GB)
- University Hospitals Plymouth NHS Trust (GB)
Publication Details
- Journal
- The Journal of Allergy and Clinical Immunology In Practice
- Published
- 2025-08-05
- DOI
- https://doi.org/10.1016/j.jaip.2025.07.041
- Citations
- 6
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.99