Upper gastrointestinal hemorrhage as a manifestation of systemic lupus erythematosus: a case report

Although systemic lupus erythematosus typically involves multiple organ systems, atypical features-such as upper gastrointestinal bleeding and recurrent pneumonia-can obscure the diagnosis and delay the initiation of appropriate treatment. In this case, despite the late start of therapy, the patient achieved full recovery. This case highlights the importance of recognizing rare manifestations of relatively common diseases and evaluating for coexisting conditions, such as subclinical hypothyroidism, which would influence disease activity, treatment response, and overall prognosis.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-08-05
DOI
https://doi.org/10.1186/s13256-025-05419-4
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

Upper gastrointestinal hemorrhage as a manifestation of systemic lupus erythematosus: a case report

Kedir Negesso Tukeni, Elsah Tegene Asefa, Kidus Tesfaye Bezabih, Mulugeta Kebede et al.
2 links
Journal of Medical Case Reports
Systemic Lupus Erythematosus Research
article

Upper gastrointestinal hemorrhage as a manifestation of systemic lupus erythematosus: a case report

Kedir Negesso Tukeni, Elsah Tegene Asefa, Kidus Tesfaye Bezabih, Mulugeta Kebede, Ermias Habte Gebremichael, Tamirat Godebo Woyimo, Ramadan Jemal Dekema
article en

Abstract

Although systemic lupus erythematosus typically involves multiple organ systems, atypical features-such as upper gastrointestinal bleeding and recurrent pneumonia-can obscure the diagnosis and delay the initiation of appropriate treatment. In this case, despite the late start of therapy, the patient achieved full recovery. This case highlights the importance of recognizing rare manifestations of relatively common diseases and evaluating for coexisting conditions, such as subclinical hypothyroidism, which would influence disease activity, treatment response, and overall prognosis.

Journal of Medical Case ReportsVol. 19(1)
Jimma University (ET)
Good health and well-being
Openalex Percentile: Top 69%
Systemic Lupus Erythematosus Research
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