ACL repair vs. reconstruction: a meta-analysis of outcomes across different tear characteristics

Anterior cruciate ligament (ACL) reconstruction remains the gold standard but carries donor-site morbidity and prolonged recovery. Modern ACL repair techniques theoretically preserve native proprioception and enable faster rehabilitation. We hypothesized that modern ACL repair would demonstrate non-inferior clinical outcomes compared to reconstruction.This meta-analysis compares clinical outcomes of primary repair versus autograft reconstruction. We systematically searched PubMed, Cochrane Library, and Web of Science (2015–2025) for comparative studies (RCTs, cohorts, case-controls) reporting ≥ 2 key outcomes (failure rate, AP knee laxity, IKDC, Lysholm, or Tegner scores) with ≥ 1-year follow-up. Pooled ORs and WMDs with 95% CIs were calculated using RevMan 5.4. Subgroup analyses (injury-to-surgery time, injury location, study design, repair technique) and GRADE assessment were performed. Fourteen studies (4 RCTs, 8 cohorts, 2 case-controls; n = 908 patients) were included (repair: n = 460; reconstruction: n = 448). Failure/Revision Rates: Repair demonstrated numerically higher failure rates (OR = 2.24, 95% CI 1.30–3.86, P = 0.004) and revision rates (OR = 2.01, 95% CI 1.21–3.33, P = 0.007) versus reconstruction.Hardware removal: increased hardware removal incidence was observed in repair groups (OR = 8.19, 95% CI 2.89–23.20, P < 0.001).AP knee laxity: reconstruction showed marginally lower AP knee laxity (WMD = 0.30, 95% CI 0.06–0.53, P = 0.01).Patient-reported outcomes: no significant differences in IKDC (WMD = 1.31,95%CI: −0.01–2.63;P = 0.05) or Tegner scores (WMD: 0.01; 95% CI: -0.28– 0.30;P = 0.94). Lysholm scores slightly favored reconstruction (WMD = 1.62,; 95% CI: 0.35–2.89;P = 0.01).Key subgroup findings: repair achieved comparable outcomes to reconstruction in: (1) RCT-designed studies, (2) Acute repairs (< 21 days post-injury). ACL repair is associated with higher failure and revision rates than reconstruction overall, but may be a viable alternative in selected patients with acute proximal tears.

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Publication Details

Journal
BMC Surgery
Published
2025-08-05
DOI
https://doi.org/10.1186/s12893-025-03101-6
Citations
1
Primary Topic
Knee injuries and reconstruction techniques
Type
article
Field-Weighted Citation Impact
2.01

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article

ACL repair vs. reconstruction: a meta-analysis of outcomes across different tear characteristics

Husen Wang, Ying Zeng, Shu Li, Bin Tang et al.
1 citations
BMC Surgery
Knee injuries and reconstruction techniques
2.01
article

ACL repair vs. reconstruction: a meta-analysis of outcomes across different tear characteristics

Husen Wang, Ying Zeng, Shu Li, Bin Tang, Hui Zheng, Nacke Daoerji
article en
1 citations

Abstract

Anterior cruciate ligament (ACL) reconstruction remains the gold standard but carries donor-site morbidity and prolonged recovery. Modern ACL repair techniques theoretically preserve native proprioception and enable faster rehabilitation. We hypothesized that modern ACL repair would demonstrate non-inferior clinical outcomes compared to reconstruction.This meta-analysis compares clinical outcomes of primary repair versus autograft reconstruction. We systematically searched PubMed, Cochrane Library, and Web of Science (2015–2025) for comparative studies (RCTs, cohorts, case-controls) reporting ≥ 2 key outcomes (failure rate, AP knee laxity, IKDC, Lysholm, or Tegner scores) with ≥ 1-year follow-up. Pooled ORs and WMDs with 95% CIs were calculated using RevMan 5.4. Subgroup analyses (injury-to-surgery time, injury location, study design, repair technique) and GRADE assessment were performed. Fourteen studies (4 RCTs, 8 cohorts, 2 case-controls; n = 908 patients) were included (repair: n = 460; reconstruction: n = 448). Failure/Revision Rates: Repair demonstrated numerically higher failure rates (OR = 2.24, 95% CI 1.30–3.86, P = 0.004) and revision rates (OR = 2.01, 95% CI 1.21–3.33, P = 0.007) versus reconstruction.Hardware removal: increased hardware removal incidence was observed in repair groups (OR = 8.19, 95% CI 2.89–23.20, P < 0.001).AP knee laxity: reconstruction showed marginally lower AP knee laxity (WMD = 0.30, 95% CI 0.06–0.53, P = 0.01).Patient-reported outcomes: no significant differences in IKDC (WMD = 1.31,95%CI: −0.01–2.63;P = 0.05) or Tegner scores (WMD: 0.01; 95% CI: -0.28– 0.30;P = 0.94). Lysholm scores slightly favored reconstruction (WMD = 1.62,; 95% CI: 0.35–2.89;P = 0.01).Key subgroup findings: repair achieved comparable outcomes to reconstruction in: (1) RCT-designed studies, (2) Acute repairs (< 21 days post-injury). ACL repair is associated with higher failure and revision rates than reconstruction overall, but may be a viable alternative in selected patients with acute proximal tears.

BMC SurgeryVol. 25(1)
Xinjiang Medical University (CN), Sixth Affiliated Hospital of Xinjiang Medical University (CN)
Xinjiang Medical University, Natural Science Foundation of Xinjiang
Openalex Percentile: Top 13%
Knee injuries and reconstruction techniques
2.01
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